ANATOMY
HOMEPAGE 
 
 
 
 
 
 
 
 
  
 
Weakness   
Practice question 1  

Which of the following statements is TRUE regarding SNAP amplitudes? 

A
are lower than normal with lesions of the ventral horn 
B
are lower than normal in a mixed (motor and sensory) peripheral nerve if the myelin associated with all 
of the axons is diseased 
C
are normal in a mixed (motor and sensory) peripheral nerve if all of the axons (versus myelin) are diseased 
D
are normal in muscle disease 
E
none of the statements are true 
 
 
 
Weakness   
Practice question 2  

Which of the following statements is TRUE regarding type grouping and group atrophy

A
occur during anterior horn disease 
B
occur during NMJ disease
C
occur during muscle disease
D
commonly occur during myasthenia gravis
E
occur during myelin degeneration of a peripheral nerve 
 
 
 
 
Weakness   
Practice question 3 

Which of the following statements is TRUE regarding a demyelinating disease? (NO axis cylinder damage) 

A
inflammation and an increase in blood CK
B
larger than normal MUPs
C
slower than normal conduction velocities
D
group atrophy 
E
decrease in CMAP amplitude
 

 

 
Weakness 
Practice question 4 

Which of the following statements is TRUE regarding a disease of  75% of all axis cylinders (not myelin) in 
a mixed (motor and sensory) peripheral nerve?

A
 normal amplitude of SNAPs and CMAPs
B
 normal conduction velocity
C
smaller than normal MUPs
D
decrement in CMAP response upon repetitive stimulation
E
absence of type grouping and group atrophy
 
 
 
 
Weakness 
Practice question 5 

Which of the following statements is TRUE

A
 myasthenia gravis is an autoimmune disease in which antibodies destroy norepinephrine receptors
B
 in myasthenia gravis, there are smaller than normal MUPs
C
in myasthenia gravis, there are lower than normal CMAP and SNAP amplitudes 
D
myasthenia gravis is caused by a defect of the neuromuscular junction
E
in myasthenia gravis, there are large MUPs 
 
           
 
Weakness 
Practice question 6 

Which of the following statements is TRUE? (ALL parts of the statement must be TRUE

A
 diseases of the neuromuscular junction never result in abnormal fatigue on exercise 
B
 in Duchenne muscle dystrophy, the patient exhibits large calves and distal muscle weakness
C
in primary muscle diseases, there are normal nerve conduction velocities, normal SNAPs, and normal CMAPs 
D
in primary muscle diseases, needle examination reveals large MUPs
E
myotonia is sustained contraction 
 
 
 
 
Weakness 
Practice question 7 

Which of the following statements is TRUE?

A
blood CK is elevated in myasthenia gravis
B
an EMG that reveals decremental CMAP responses on repeated nerve stimulation 
indicates a disease of the muscle
C
type I muscle fibers are slow contracting 
D
type grouping occurs in muscular dystrophy
E
inflammation is not indicative of myopathy 
 
 
 
Weakness 
Practice question 8 

Which of the following statements is TRUE regarding distal polyneuropathies?

A
 results in increased tendon reflexes
B
 results in only motor deficits
C
sensory loss = glove and stocking distribution
D
effect is greater on proximal muscles than on distal
E
never seen in diabetes 
 
 
 
Weakness 
Practice question 9 

Which of the following statements is TRUE

A
 a SNAP represents the action potential of a single axon 
B
 a CMAP represents the action potential of a single muscle fiber
C
a motor unit is a single neuron in the ventral horn and all of the muscle fibers that it innervates
D
a MUP represents the action potential of an entire muscle
E
myasthenia gravis is a presynaptic defect 
 
 
 
Weakness 
Practice question 10 

Which of the following statements is TRUE regarding the result of the lesion (shaded area) shown in the drawing below?

A
 increase in amplitude of CMAPs upon stimulation of innervating nerve 
B
 decrease in conduction velocity of innervating nerve
C
decremental CMAP upon repetitive stimulation of innervating nerve
D
increase in MUPs
E
increase in CK
 
 
 
Weakness 
Practice question 11 

Which of the following statements is FALSE regarding the result of the lesion (shaded area) shown in the 
drawing below? Not all of the fibers are dead and both the axis cylinder and myelin are affected. 
 

A
type grouping
B
 group atrophy
C
decrease in CMAP amplitude
D
decrease in MUPs
E
normal conduction velocities
 
 
 
Weakness 
Practice question 12 

Which of the following statements is TRUE regarding the result of the lesion shown in the drawing below? 
ALL myelin is affected (gone) in the involved structures. 
 

A
type grouping
B
group atrophy
C
decrease in CMAP amplitude
D
decrease in size of MUPs
E
decrease in conduction velocities 
 
 
 
Weakness 
Practice question 13 

Which of the following statements is FALSE regarding the result of the lesion shown in the drawing below? 
Only the axis cylinder (not the myelin) is affected in the involved structures. 
 

A
type grouping
B
 group atrophy
C
decrease in conduction velocities 
D
increase in size of MUPs
E
normal CK 
 
 
 
Weakness  
Practice question 14 

Which of the following statements is FALSE regarding the muscle (and associated nerves) illustrated below? 
 

A
decreased CMAP
B
group atrophy
C
decrease in conduction velocities
D
increase in size of MUPs
E
normal CK 
 
 
 
Weakness 
Practice question 15 

Which of the following statements is FALSE regarding the fiber illustrated below? 
 

A
is a hypomyelinated fiber
B
fiber conducts more slowly than normal
C
fiber can convey an action potential
D
the axon will sprout in the associated muscle
E
the MUP associated with this fiber is normal 
 
 
 
Weakness 
Practice question 16 

Which of the following statements is TRUE regarding the information shown in the drawing below? 
 

A
would result from a lesion in the ventral horn
B
would result from a demyelinating disease
C
could be caused by antibodies to acetylcholine receptors
D
could result from a lesion of the lateral corticospinal tract (LCST)
E
patient would have an increase in CK 
 
 
 
Weakness 
Practice question 17 

Fill in the blanks in the chart below.. 
 
 

ANSWER to question 17
 
Back to Clinical spinal cord